Medical aesthetics - Exposure Total Sunblock Cream Detailed Information

PRODUCT DETAILED INFORMATION

exposure® total sunblock

DESCRIPTION
Exposure® Total Sunblock Cream is an original formulation that provides complete protection from sun radiation including UV rays, with SPF 30+ (for external use only).

MAIN INGREDIENTS
Aqua, titanium dioxide, cyclopentasiloxane, zinc oxide, polyglyceryl-4 isostearate, cetyl peg/ppg-10/1 dimethicone, hexyl laurate, diethyl butamido triazone, c12-15 alkyl benzoate, glycerin, mineral oil, lanolin alcohol, benzophenone-3, sodium chloride, dimethicone, phenoxyethanol, disodium edta.

INDICATIONS
Complete protection from sun light and radiation, including UV rays. Exposure® Total Sunblock Cream is recommended for:

sun sensitive skin
prevention of skin ageing (photodamage)
skin laser / ipl post-treatment care (including resurfacing, hair removal, thread vein removal and rejuvenation)
chemical peel post-treatment care
complement to skin lightening treatments

PROPERTIES
Exposure® Total Sunblock Cream is an original formula that uses an innovative microdispersion of the main active ingredients, titanium dioxide, zinc oxide, and DB Triazone. This results in a dermatological broad-spectrum sunscreen that does not blanches the skin, and reflects effectively all sun light and radiation, with unique properties:

total reflection of sunlight
total reflection of UV radiation (including UVA and UVB)
spf 30+
australian standard passed
intensive moisturising
PABA-free
non-allergenic
non-greasy
non-blanching

DIRECTIONS
Suitable for all skin types. Apply liberally and evenly to all uncovered areas 15 minutes before exposing the skin to the sun. Reapply frequently during prolonged sun exposure (every 2-3 hours) and always after swimming or towel drying.
Exposure® Total Sunblock Cream is suitable for use in face and body.

WARNING
Topical use only. Do not apply to eyes, mucose membranes and/or open wounds.
Some patients experience breakouts any time they change their skin care regimen. Skin reactions to any new topical product, though rare, are likely to occur within the first few days of use. If any reaction occurs, wash the product off and discontinue use.

CONTRAINDICATIONS
Prior history of sensitivity or allergic reaction to this product or any of its ingredients.

ADVERSE REACTIONS
No systemic adverse reactions have been reported. In rare cases, hypersensitivity (localized contact dermatitis) may occur: cream application should be discontinued and the physician notified immediately.

KEEP OUT OF THE REACH AND SIGHT OF CHILDREN

Not tested on animals
Manufactured in the EC for Medical Aesthetics Ltd., London, UK.

BIBLIOGRAPHY
1. Investigation of the stability of coated titanium microparticles used in sunscreens. Lademann J, Weigmann H, Schafer H, Muller G, Sterry W. Skin Pharmacol Appl Skin Physiol. 2000 Sep-Oct;13(5):258-64.
2. Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice. Lademann J, Weigmann H, Rickmeyer C, Barthelmes H, Schaefer H, Mueller G, Sterry W. Skin Pharmacol Appl Skin Physiol. 1999 Sep-Oct;12(5):247-56.
3. The effects of manganese doping on UVA absorption and free radical generation of micronised titanium dioxide and its consequences for the photostability of UVA absorbing organic sunscreen components. Wakefield G, Lipscomb S, Holland E, Knowland J.
4. Sunscreens--the ultimate cosmetic. Wolf R, Matz H, Orion E, Lipozencic J. Acta Dermatovenerol Croat. 2003;11(3):158-62.
5. Analytical methodologies for atomic spectrometric determination of metallic oxides in UV sunscreen creams. Salvador A, Pascual-Marti MC, Adell JR, Requeni A, March JG. J Pharm Biomed Anal. 2000 Mar;22(2):301-6.
6. Integration of zinc oxide nanoparticles into transparent poly(butanediolmonoacrylate) via photopolymerisation. Althues H, Simon P, Philipp F, Kaskel S. J Nanosci Nanotechnol. 2006 Feb;6(2):409-13.
7. The effect of sunscreen on skin elastase activity induced by ultraviolet-A irradiation. Tsukahara K, Moriwaki S, Hotta M, Fujimura T, Sugiyama-Nakagiri Y, Sugawara S, Kitahara T, Takema Y. Biol Pharm Bull. 2005 Dec;28(12):2302-7.
8. Distribution of sunscreens on skin. Schulz J, Hohenberg H, Pflucker F, Gartner E, Will T, Pfeiffer S, Wepf R, Wendel V, Gers-Barlag H, Wittern KP. Adv Drug Deliv Rev. 2002 Nov 1;54 Suppl 1:S157-63.
9. Studies on zinc in wound healing. Agren MS. Acta Derm Venereol Suppl (Stockh). 1990;154:1-36.
10. Determination of sixteen UV filters in suncare formulations by high-performance liquid chromatography. Schakel DJ, Kalsbeek D, Boer K.J Chromatogr A. 2004 Sep 17;1049(1-2):127-30.
11. Determination of the UV filters worldwide authorised in sunscreens by high-performance liquid chromatography. Use of cyclodextrins as mobile phase modifier. Chisvert A, Pascual-Marti MC, Salvador A. J Chromatogr A. 2001 Jul 6;921(2):207-15.
12. Skin penetration and sun protection factor of five UV filters: effect of the vehicle. Chatelain E, Gabard B, Surber C. Skin Pharmacol Appl Skin Physiol. 2003 Jan-Feb;16(1):28-35.
13. Sun safety: avoiding noonday sun, wearing protective clothing, and the use of sunscreen. Turner M. J Natl Cancer Inst. 1998 Dec 16;90(24):1854-5.
14. Preventing excess sun exposure. Emmons KM, Colditz GA. J Natl Cancer Inst. 1999 Aug 4;91(15):1269-70.
15. Daily relations with UV and prevention of photoaging of skin -- introduction to the topic. Luger TA, Beissert S. J Dtsch Dermatol Ges. 2005 Sep;3 Suppl 2:S1-2.

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