Medical aesthetics - Exposure dermatological eye contour cream with 5% eyeseryl

PRODUCT DETAILED INFORMATION

exposure® dermatological eye contour cream
with 5% eyeseryl®

DESCRIPTION
Exposure® Dermatological Eye Contour Cream with 5% Eyeseryl® is an original tetrapeptide based formulation for the reduction of puffy eyebags and dark circles around the eyes (for external use only).

MAIN INGREDIENTS
Aqua, hydrolyzed soy protein, acetyl tetrapeptide-5, glycerin, hydroxyethylcellulose, peg/ppg-14/4 dimethicone, mineral oil, hydrogenated polyisobutene, stearyl heptanoate, imidazolidinyl urea, mica (and) titanium dioxide, bisabolol, disodium edta, methylchloroisothiazolinone, methylisothiazolinone, phenoxyethanol.

INDICATIONS
Treatment of periorbital oedema and elastosis (puffy eyebags), fine lines and wrinkles, dark circles and in general to improve skin elasticity and smoothness around the eyes.

PROPERTIES
Exposure® Dermatological Eye Contour Cream with 5% Eyeseryl® uses a patented original formula. Its potent effects have shown in clinical trials to reduce eye puffiness and improve the appearance of the skin in only 15 days, by the following mechanisms of action:

fast draining effect: ACE (Angiotensin I Converting Enzyme) inhibitory activity improves blood circulation
anti oedema effect: inhibition of vascular permeability
eyelift effect: enhancement of skin elasticity and smoothness

DIRECTIONS
Apply to affected areas once a day in the morning for the first week, and then twice a day, or as directed by your Doctor.
Apply directly after cleanser, thoroughly massaging on a clean, dry skin.

WARNING
Topical use only. Do not apply to eyes, mucose membranes and/or open wounds.
Some patients experience breakouts any time they change their skin care regimen. Skin reactions to any new cream, though rare, are likely to occur within the first few days of use. If any reaction occurs, wash the product off and discontinue use.
Eyeseryl® has been tested for ocular irritation and is considered non-irritatnt.

CONTRAINDICATIONS
Prior history of sensitivity or allergic reaction to this product or any of its ingredients.

ADVERSE REACTIONS
No systemic adverse reactions have been reported. In rare cases, hypersensitivity (localized contact dermatitis) may occur: cream application should be discontinued and the physician notified immediately.

KEEP OUT OF THE REACH AND SIGHT OF CHILDREN

Not tested on animals
Manufactured in the EC for Medical Aesthetics Ltd., London, UK

BIBLIOGRAPHY
1. Eyeseryl: In vitro citotoxicity assay on keratinocites. F. Reig Isart. Dept. of Mollecular Pathology and Experimental Therapeuthic (ICCC-CSIC). Barcelona, May 2004.
2. Evaluation of the potential ocular irritation of Eyeseryl through Het-Cam test. Departamento de Quimica de Peptidos y Proteinas, Instituto de Investigaciones Quimicas y Ambientales, CSIC, Barcelona, March 2004.
3. Human skin compatibility of a new cosmetic product (Eyeseryl); patch test with dermatological control. C. Pascual, S. Palacio, Sept. 2004. Evic Hispania for Lipotec, S.A.
4. Evaluation of antiinflammatory activity of a chamomile extract topical application. Tubaro A, Zilli C, Redaelli C, Della Loggia R. Planta Med. 1984 Aug;50(4):359.
5. The role of flavonoids in the antiinflammatory activity of Chamomilla recutita. Della Loggia R, Tubaro A, Dri P, Zilli C, Del Negro P. Prog Clin Biol Res. 1986;213:481-4.
6. What causes the dark circles that sometimes appear under my eyes? Mayo Clin Womens Healthsource. 2003 Jun;7(6):8.
7. Puffy eyes: a multi-factoral cosmetic problem needs a multi-faceted solution. Lintner K, Mas-Chamberlin C, Mondon P, Peschard O, Lamy F. J Cosmet Sci. 2004 Mar-Apr;55(2):226-7.
8. Cosmetic care of the facial skin. Kretova NM. Feldsher Akush. 1968 Sep;33(9):58-60.
9. Foundations of cosmetic care of the facial skin. Astvatsaturov KR, Kol'guenenko II. Med Sestra. 1966 Jun;25(6):55-8.
10. Cosmetic surgery of the eyelids and forehead. Hollander MM. Eye Ear Nose Throat Mon. 1958 Jul;37(7):452-6 passim.
11. Corrective cosmetics are effective for women with facial pigmentary disorders. Balkrishnan R, McMichael AJ, Hu JY, Camacho FT, Kaur M, Bouloc A, Rapp SR, Feldman SR. Cutis. 2005 Mar;75(3):181-7.
12. Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. Elmore AR. Int J Toxicol. 2005;24.
13. Clinical effects of cosmetic vehicles on skin. Fluhr JW, Rigano L. J Cosmet Sci. 2004 Mar-Apr;55(2):189-205.
14. In vivo skin penetration studies of camomile flavones. Merfort I, Heilmann J, Hagedorn-Leweke U, Lippold BC. Pharmazie. 1994 Jul;49(7):509-11.
15. Evaluation of antiinflammatory activity of a chamomile extract topical application. Tubaro A, Zilli C, Redaelli C, Della Loggia R. Planta Med. 1984 Aug;50(4):359.

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